Tobias J. Erb

Research Area

Tobias Erb’s research interests are the microbial carbon cycle, in particular the biochemistry and synthetic biology of carbon dioxide conversion. The Erb lab centers on the discovery, the function and the design of novel CO2 converting enzymes from bacteria, algae and plants and their use in artificial photosynthesis, as well as the bottom-up design of complex metabolic networks and artificial cells.

Expertise

synthetic microbiology
CO2-fixation
protein engineering
biochemistry
microbial metabolism
metabolic networks
microbial metabolism
artificial photosynthesis
global carbon cycle
minimal and artificial cells

Recent Publications, Last 3 Years

1. Schada von Borzyskowski L, Severi F, Krüger K, Hermann L, Gilardet A, Sippel F, Pommerenke B, Claus P, Cortina NS, Glatter T, Zauner S, Zarzycki J, Fuchs BM, Bremer E, Maier UG, Amann RI, Erb TJ. (2019) Marine Proteobacteria metabolize glycolate via the ß-hydroxyaspartate cycle. Nature 575:500-504.

2. Stoffel GMM, Saez DA, DeMirci H, Vögeli B, Rao Y, Zarzycki J, Yoshikuni Y, Wakatsuki S, Vöhringer-Martinez E, Erb TJ. (2019) Four amino acids define the CO2 binding pocket of enoyl-CoA carboxylases/reductases. Proc Natl Acad Sci USA 116:13964-13969.

3. Schwander T, Schada von Borzyskowski L, Burgener S, Cortina NS, Erb TJ. (2016) A synthetic pathway for the fixation of carbon dioxide in vitro. Science. 354:900-904.

http://www.mpi-marburg.mpg.de/erb/